Asociación entre litiasis vesicular y resistencia a la insulina en pacientes operados en el CHMH

Abstract

Definición del problema. ¿Cuál es la asociación entre litiasis vesicular y resistencia a la insulina en pacientes operados en el CHMH? Metodología de la investigación. Es estudio prospectivo, longitudinal, comparativo y descriptivo. Se asignan a dos grupos: uno con colelitiasis y el otro sin colelitiasis. Pacientes que acuden a la consulta externa y se programan de forma electiva para resolución quirúrgica, se les realiza medición de glucosa, insulina basal, perfil de lípidos, presión arterial, peso y talla. Ninguno con diagnóstico de diabetes tipo 2, hipertensión arterial ni dislipidemia. Con programa SPSS se realiza comparación de ambos grupos con prueba de U de Mann Whitney. Resultados. De un total de 49 pacientes de ambos grupos, el grupo con colelitiasis conformado por 5 hombres y 27 mujeres y el grupo sin colelitiasis 10 hombres y 7 mujeres. No existe diferencia estadísticamente significativa en las variables de peso, IMC, insulina basal, glucosa, colesterol, HDL y LDL; existe diferencia estadísticamente significativa en las variables edad, estatura, triglicéridos y en el índice de HOMA. Conclusiones. El grupo con colelitiasis sin diabetes tipo 2, sin hipertensión arterial y sin dislipidemia presentan mayor resistencia a la insulina en comparación con el grupo sin litiasis vesicular.

Defining the problem. What is the relation between gallstone disease and insulin resistance in patients operated at Centenario Hospital Miguel Hidalgo? Methodology. This is a prospective, longitudinal, comparative and descriptive clinical study. One with and another without cholelithiasis were assigned to groups. Patients were attended the outpatient clinic and scheduled for elective surgical resolution, in the preoperative workup were measured performed measuring glucose, basal insulin, lipid profile, blood pressure, weight and height. None diagnosed with type 2 diabetes, hypertension and dyslipidemia were included in this study. The stadistical analysis of the data were performed with Statistical Package for the Social Sciences program comparison of the two test groups with Mann Whitney U was performed. Results. 49 patients were included in this study, the group with cholelithiasis consists of 5 men and 27 women and 10 men and 7 women group without cholelithiasis. There is no statistically significant difference in the variables of weight, BMI, basal insulin, glucose, cholesterol, HDL and LDL , there is statistically significant difference in the variables age, height , triglycerides and HOMA index . Conclusions. The group with cholelithiasis without type 2 diabetes, without hypertension and without dyslipidemia have greater insulin resistance compared with the group without gallstones