RESUMEN
INTRODUCCIÓN
La Hipertensión arterial sistémica (HAS) es de las enfermedades crónicas de mayor prevalencia en México ya que afecta al 30.8 % de la población de entre 20 a 69 años de edad
MATERIAL Y METODOS
Este estudio es Observacional, Retrospectivo y Comparativo, con expedientes de pacientes que padecen hipertensión arterial sistémica que acudieron a consulta de medicina interna con el diagnostico de hipertensión arterial sistémica que se encontraban con el tratamiento con tiazidas asociados a I.E.C.AS, versus Calcioantagonistas asociados a tiazidas
RESULTADOS
La muestra obtenida fueron 99 expedientes de pacientes que se encontraban bajo dichos antihipertensivos , La eficacia que reporto en comparación de ambos grupos fue la siguiente: en el grupo de IECAS mas tiazidas se encontraron 31 expedientes de pacientes en control y 18 no controlados, en el grupo de calcioantagonitas 31 controlados y 19 no controlados con una p= 0.531, en donde no hubo alguna significancia entre dar tratamiento con un grupo versus el otro
CONCLUSION Y DISCUSIÓN
En 2 diferentes estudios como (CAPPP,ACOMPLISH,) donde los resultados son similares al estudio realizado , con el grupo de antihipertensivos citados El estudio que se realizo en donde no hubo diferencia significativa estadística , sabemos que tiene menos peso, que los estudios prospectivos, sin embargo al comparar con la literatura mundial de estudios similares, encontramos que existe conclusiones parecidas en los resultados, comparados con nuestro estudios, por lo que sugerimos en base a los resultados usar como antihipertensivos de primera línea la combinación de I.E.C.A.S mas tiazidas por su eficacia así como bajo costo ,accesibilidad
ABSTRACT
Systemic hypertension (SH) is the most prevalent chronic diseases in Mexico because it affects 30.8% of the population aged 20 to 69 years old
MATERIAL AND METHODS
This study is an observational, retrospective, comparative study, the location of development in the general hospital of the third millennium health secretary Aguascalientes State, Records of patients with hypertension who attended the clinic of internal medicine at Hospital Third Millennium. Records of patients with a diagnosis of hypertension who were with thiazide therapy associated with ACE inhibitors. Records of patients with a diagnosis of hypertension who were treated with thiazides associated with calcium
RESULTS
the sample obtained were 99 cases of patients were under antihypertensive these, 49 patient records are handled with inhibitors of angiotensin-converting enzyme more thiazide, the second group was compared were 50 cases of patients who were treated with calcium more thiazide, the duration of hypertension was 7 years follow-up time in the outpatient internal medicine was 8 months with a value of P = 0.036.
DISCUSSION
In various studies as Project 2 (CAPPP, acomplish,) as a group to administer medicine there was no variation in blood pressure control
CONCLUSION
The study was conducted in which there was no statistically significant difference, we know that you are underweight, prospective studies, however when compared to the world literature of similar studies, we found that there similar conclusions on the results, compared with our studies, therefore suggest based on the results used as first line antihypertensives the combination of ACE inhibitors but their effectiveness thiazides and low cost, accessibility.
